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Zoon’s Balanitis (Balanitis Circumscripta Plasmacellularis) – a Case Report with a Review of Literature
Ivanka Temelkova,
Valentina Broshtilova,
Svetlana Bezhanova,
Atanas Batashki,
Yoanna Velevska,
Petar Vatov,
Irina Iungareva,
Sonya Marina
Issue:
Volume 6, Issue 2, December 2023
Pages:
14-17
Received:
13 July 2023
Accepted:
2 August 2023
Published:
22 August 2023
Abstract: Zoon's balanitis or balanitis circumscripta plasmacellularis is a rare, idiopathic, chronic, benign, inflammatory disease of the genital mucosa of non-sexually transmitted nature. Etiopathogenesis is not fully understood, but the moist environment and chronic irritation are considered as important triggers. It occurs mainly in uncircumcised middle- and elderly men, but there are single cases in circumcised men. Affects the glans penis and foreskin. It is also rarely seen in women, such as Zoon's vulvitis, with predilectation involvement of labia minora. The article presented an overview of epidemiology, clinical performance, histopathological characteristics, diagnostic criteria and diagnostic methods of Zoon's balanitis. In addition, the differential diagnosis of the disease is discussed. Treatment methods are considered and circumcision is highlighted as the "gold standard" and first choice. We present a 53-year-old man with a well-circumscribed erythematous plaques on the glans penis and the inner surface of the foreskin from 10 years. Histologically plasmocyte infiltrate is established. Based on the correlation of history, dermatological status and histopathological result was diagnosed Zoon's balanitis. Conservative topical therapy was our preferred way of treatment. On an outpatient basis, we recommended personal genital hygiene, mometasone furoate cream 0.1% for 2 weeks and tacrolimus 0.1% ointment for 1 month. A control examination after 1 and a half months found a good clinical result with mild residual erythema. The patient was explained both the need for regular clinical and histological monitoring due to the carcinogenic potential of the lesions and the option of therapeutic circumcision.
Abstract: Zoon's balanitis or balanitis circumscripta plasmacellularis is a rare, idiopathic, chronic, benign, inflammatory disease of the genital mucosa of non-sexually transmitted nature. Etiopathogenesis is not fully understood, but the moist environment and chronic irritation are considered as important triggers. It occurs mainly in uncircumcised middle-...
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Fournier's Gangrene - A Case Report with a Review of the Literature
Hristo Mangarov,
Valentina Broshtilova,
Atanas Batashki,
Svetlana Bezhanova,
Yoanna Velevska,
Petar Vatov,
Irina Yungareva,
Sonya Marina
Issue:
Volume 6, Issue 2, December 2023
Pages:
18-23
Received:
14 August 2023
Accepted:
4 September 2023
Published:
13 September 2023
Abstract: Fournier's gangrene is a rare form of necrotizing fasciitis, also known as "flesh-eating disease." It cause extensive necrosis of skin, fascia, and subcutaneous of the external genitalia, perineal and perianal areas. The etiology is usually polymicrobial. Initial dermatological symptoms may be missing or mimicking erysipelas, cellulite or abscess. The disease is life-threatening with fulminant onset and prominent intoxication symptoms. Early diagnosis, complex treatment and urgent surgical debridement are crucial in reducing lethal outcome. We describe a case of a 38-year-old man with fever, erythema, edema and severe pain in his testicles and perineum 4 days before hospitalization. He was with poor general condition. The patient had a history of recent Covid-19 infection that worsened his metabolic syndrome and chronic pulmonary obstructive disease. Blood tests showed leukocytosis and extremely elevated C-reactive protein, and microbiological plating - beta streptococci and Staphylococcus aureus. Broad-spectrum antibiotics, aggressive debridement, adequate resuscitation and local treatment of the wound provided fast recovery and favourable outcome. An overview of the epidemiology, risk factors, etiological microorganisms, clinical picture, systemic and local complications, psychological problems, laboratory and imaging diagnostic methods of Fournier's gangrene is presented. Fournier’s gangrene and necrotizing fasciitis clinical risk assessment systems are also highlighted. Most appropriate therapeutic modalities are comprehensively discussed.
Abstract: Fournier's gangrene is a rare form of necrotizing fasciitis, also known as "flesh-eating disease." It cause extensive necrosis of skin, fascia, and subcutaneous of the external genitalia, perineal and perianal areas. The etiology is usually polymicrobial. Initial dermatological symptoms may be missing or mimicking erysipelas, cellulite or abscess. ...
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Research Article
Surgical Treatment of Skin Cancers of the Head and Neck at the DONKA Surgical Oncology Unit
Bah Malick,
Keita Mamady,
Toure Alhassane Ismael,
Cisse Kalil,
Souare Mamadou Bobo,
Conde Ibrahima Kalil,
Traore Bangaly
Issue:
Volume 6, Issue 2, December 2023
Pages:
24-28
Received:
5 September 2023
Accepted:
12 October 2023
Published:
28 October 2023
Abstract: Objective: To improve the surgical treatment of head and neck skin cancers. Materials and methods: This was a retrospective descriptive cohort study examining the sociodemographic, anatomopathological, therapeutic and evolutionary aspects of patients with head and neck skin cancer. Results: 148 patients (65.2%) were histologically confirmed and 43 (29.1%) underwent surgery. The mean age was 33 ± 16 years. The average time to treatment was 6 months. There were 10 (22.0%) stage III cases. The most typical histological type was squamous cell carcinoma (97.7%), of which 18 cases (41.9%) had a tumor size > 4 cm. Wide resection was performed in 88.4% of cases and surgical wound closure was achieved by flap grafting in 55.8% of cases. Healing was normal in 53.5% of cases. After a mean follow-up of 16 ± 22 months, overall survival at 12 months was 44%. 13 patients (30.2%) are still alive. Conclusions: This study shows that only a small number of head and neck skin cancer patients are operated on in the oncology department of Conakry University Hospital. Ongoing training of healthcare professionals and dermatological surveillance for primary and secondary prevention of skin cancer in people with albinism may help to improve outcomes for people with skin cancer and improve the quality of care for head and neck skin cancer.
Abstract: Objective: To improve the surgical treatment of head and neck skin cancers. Materials and methods: This was a retrospective descriptive cohort study examining the sociodemographic, anatomopathological, therapeutic and evolutionary aspects of patients with head and neck skin cancer. Results: 148 patients (65.2%) were histologically confirmed and 43 ...
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Research Article
A Congenital Purple Plaque, a Case Report with the Review of Literature
Tayyiba Nasreen,
Fiona Lynch,
Ruth Law,
Sinead Collins
Issue:
Volume 6, Issue 2, December 2023
Pages:
29-32
Received:
30 August 2023
Accepted:
20 October 2023
Published:
9 November 2023
Abstract: Dermatofibrosarcoma protruberans (DFSP) is an uncommon, locally aggressive tumour arising. it accounts for 0.1% of all malignancies. Although it can present any time from the neonatal period onwards, paediatric cases are rare, and account for 6% of all DFSP. The cause of dermatofibrosarcoma protuberans is not known but, injury to the skin in the affected location could be a risk factor. It can occur within pre-existing scars and tattoos. Clinical presentation is typically as a solitary plaque or nodule most often on the trunk or extremities. The initial lesion is a skin coloured, slow growing plaque which develops a red /brown colour and nodular surface. but tends to recur after excision. It rarely spreads to other sites beyond the skin. The article presents an overview of epidemiology, distinct clinical evolution, histopathological characteristics, gene involvement and differential diagnosis of DFSP. Management should be multi-disciplinary, with a view to maximising tumour clearance while minimising tissue loss. We present A 3-year-old girl was referred to dermatology for a slow-growing painless lesion on her left lower abdomen. The lesion had been present since birth. At ten months-of-age a paediatrician made a clinical diagnosis of infantile haemangioma. Examination of the skin of the left lower abdominal quadrant revealed a 5×3 cm ill-defined pink plaque containing multiple discrete violaceous nodules. Histology revealed a dermal infiltrate of monomorphic spindled cells arranged in a storiform pattern with no cytological atypia, Immunohistochemistry staining was positive for CD34. Following multi-disciplinary review, she was referred to plastic surgery for wide local excision. The indolent behaviour of early DFSP can lead to a delay in diagnosis. Also, they are commonly misdiagnosed as vascular malformations children. It is recommended that patients undergo surveillance for local recurrence for longer than five years following primary excision.
Abstract: Dermatofibrosarcoma protruberans (DFSP) is an uncommon, locally aggressive tumour arising. it accounts for 0.1% of all malignancies. Although it can present any time from the neonatal period onwards, paediatric cases are rare, and account for 6% of all DFSP. The cause of dermatofibrosarcoma protuberans is not known but, injury to the skin in the af...
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Case Report
Polychondritis Recidivans – A Case Report with a Review of the Literature
Irina Yungareva,
Valentina Broshtilova,
Aleksandar Trenovski,
Yoanna Velevska,
Petar Vatov,
Sonya Marina*
Issue:
Volume 6, Issue 2, December 2023
Pages:
33-38
Received:
16 November 2023
Accepted:
4 December 2023
Published:
11 December 2023
Abstract: Polychondritis recidivans is a rare immune-mediated autoimmune, multisystemic disease. It proceeds with recurrent inflammation of both cartilage tissue, mainly the ears, nose, larynx, tracheobronchial tree, ribs and joints, as well as the proteoglycan-rich tissues of the heart valves, blood vessels and eyes. The clinical picture is diverse. Symptoms often overlap with other diseases and diagnosis is delayed. Late diagnosis is the main cause of complications, and life-threatening damage to the affected structures. Polychondritis recidivans may be self-contained or associated with other autoimmune diseases, vasculitis, or hematological disorders. The diagnosis is clinical. The main manifestation of diagnostic value is chondritis with sequential or simultaneous involvement of several cartilage organs. There is no specific laboratory test for the disease. A cornerstone of therapy is glucocorticoids. With severe course, immunosuppressants are also used, and recently biological agents. We describe a case of a 51-year-old woman with repeated recurrences of moving inflammation of the ear cartilage, accompanied by arthritis, severely reduced hearing, hoarseness, conjunctivitis and episcleritis, and CNS symptoms. Blood tests showed leukocytosis and elevated C-reactive protein. Polychondritis recidivans is diagnosed based on the diagnostic criteria of L. P. McAdam et al., J. M. Damiani and H. L. Levine and C. J. Michet et al. Dramatic improvement from methylprednisolone treatment supported the diagnosis. An overview of the epidemiology, pathogenesis, clinical picture, complications, laboratory and imaging diagnostic methods, and treatment of polychondritis recidivans are presented.
Abstract: Polychondritis recidivans is a rare immune-mediated autoimmune, multisystemic disease. It proceeds with recurrent inflammation of both cartilage tissue, mainly the ears, nose, larynx, tracheobronchial tree, ribs and joints, as well as the proteoglycan-rich tissues of the heart valves, blood vessels and eyes. The clinical picture is diverse. Symptom...
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