Introduction: Pressure injuries represent a significant and prevalent public health problem in bedridden and institutionalized patients. The correct management of pressure injuries is essential for preventing complications, enhancing patient well-being, and reducing the overall burden on healthcare systems. It underscores the importance of a holistic and patient-centered approach to wound care. Preventive measures and the action of a multidisciplinary team are essential to the correct treatment of pressure injuries. There are multiple active dressings and topical solutions to treat and protect the wounds, among them the hyperoxygenated fatty acids, such as Abzolem®. Objective: Evaluate and verify the effectiveness and safety of the use of Abzolem® in the treatment of patients with pressure injuries grade I and II. Materials and methods: an exploratory study was carried out on 6 patients residing in a long-term establishment in Santiago of Chile with grade I and II pressure injuries in which Abzolem® was used for twice-daily dressings. Results: The use of Abzolem® led to a significant improvement in grade I pressure injuries in 10 ± 3 days and grade II pressure injuries in 15 ± 3 days, without related adverse events and with good tolerance by patients. Conclusion: The use of hyperoxygenated fatty acids, such as Abzolem® corresponds to a safe therapeutic alternative, easy to apply, and effective in the treatment of grade I and II pressure injuries.
| Published in | International Journal of Clinical Dermatology (Volume 7, Issue 1) |
| DOI | 10.11648/j.ijcd.20240701.12 |
| Page(s) | 6-10 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Pressure Ulcers, Pressure Injuries, Healing, Wounds, Institutionalized Patients
| [1] | Jiang Q, Li X, Qu X, Liu Y, Zhang L, Su C, Guo X, Chen Y, Zhu Y, Jia J, Bo S, Liu L, Zhang R, Xu L, Wu L, Wang H, Wang J. The incidence, risk factors and characteristics of pressure ulcers in hospitalized patients in China. Int J Clin Exp Pathol. 2014; 7(5): 2587-94. |
| [2] | Pancorbo Hidalgo PL, García Fernández FP. Estudio nacional de prevalencia de UPP y otras lesiones relacionadas con la dependencia. In: XII Simposio Nacional sobre Úlceras por Presión y Heridas Crónicas. Gerokomos; 2019(30). 76-86. |
| [3] | Kosiak M. Etiology of decubitus ulcers. Arch Phys Med Rehabil. 1961; 42: 19-29. |
| [4] | García -Fernández FP, Soldevilla-Ágreda JJ, Pancorbo-Hidalgo PL, Verdú Soriano J, López-Casanova P, Rodríguez-Palma M. Clasificación-categorización de las lesiones relacionadas con la dependencia. Serie Documentos Técnicos GNEAUPP n.° II. Grupo Nacional para el Estudio y Asesoramiento en Úlceras por Presión y Heridas Crónicas. Logroño 2014. |
| [5] | Stausberg J, Kiefer E. Classification of pressure ulcers: a systematic literature review. Stud Health Technol Inform. 2009; 146: 511-515. |
| [6] | Sugathapala RDUP, Latimer S, Balasuriya A, Chaboyer W, Thalib L, Gillespie BM. Prevalence and incidence of pressure injuries among older people living in nursing homes: A systematic review and meta-analysis. Int J Nurs Stud. 2023. 14; 148: 104605. https://doi.org/10.1016/j.ijnurstu.2023.104605 |
| [7] | Sardo PMG, Teixeira JPF, Machado AMSF, Oliveira BF, Alves IM. A systematic review of prevalence and incidence of pressure ulcers/injuries in hospital emergency services. J Tissue Viability. 2023; 32(2): 179-187. https://doi.org/10.1016/j.jtv.2023.02.001 |
| [8] | Monsonís-Filella B, Gea-Sánchez M, García-Martínez E, Folguera-Arnau M, Gutiérrez Vilaplana JM, Blanco-Blanco J. Improving risk assessment and prevention of pressure injuries during the implementation of a best practice clinical guideline. Enferm Clin (Engl Ed). 2021; 31(2): 114-119. https://doi.org/10.1016/j.enfcli.2020.10.027 |
| [9] | Kandi LA, Rangel IC, Movtchan NV, Van Spronsen NR, Kruger EA. Comprehensive Management of Pressure Injury: A Review. Phys Med Rehabil Clin N Am. 2022; 33(4): 773-787. https://doi.org/10.1016/j.pmr.2022.06.002. PMID: 36243469. |
| [10] | Kramer A., Dissemond J., Kim S., et al: Consensus on Wound Antisepsis: Update 2018. Skin Pharmacol Physiol. 2018; 31: 28-58. |
| [11] | Segovia Gómez T, Bermejo Martínez M, Molina Silva R, Rueda López J, Torra i Bou JE. Cuidado de la piel y úlceras por presión. Los ácidos grasos hiperoxigenados en la prevención de UPP y el tratamiento de lesiones de estadio I [Skin care and pressure ulcer. Hyperoxygenated fatty acids in the prevention of pressure ulcers and treatment of stage I lesions]. Rev Enferm. 2001; 24(9): 18-22. |
| [12] | Martínez Sánchez G. Racional científico para las aplicaciones médicas de los aceites ozonizados, actualización. Ozono Therapy Global Journal. 2021(11): 201-237. |
| [13] | Xiao W, Tang H, Wu M, Liao Y, Li K, Li L, Xu X. Ozone oil promotes wound healing by increasing the migration of fibroblasts via PI3K/Akt/mTOR signaling pathway. Biosci Rep. 2017 Nov 9; 37(6): BSR20170658. https://doi.org/10.1042/BSR20170658 |
| [14] | Kim HS, Noh SU, Han YW, Kim KM, Kang H, Kim HO, Park YM. Therapeutic effects of topical application of ozone on acute cutaneous wound healing. J Korean Med Sci. 2009; 24(3): 368-74. https://doi.org/10.3346/jkms.2009.24.3.368 |
| [15] | Sechi LA, Lezcano I, Nunez N, Espim M, Duprè I, Pinna A, Molicotti P, Fadda G, Zanetti S. Antibacterial activity of ozonized sunflower oil (Oleozon). J Appl Microbiol. 2001; 90(2): 279-84. https://doi.org/10.1046/j.1365-2672.2001.01235.x |
| [16] | Takeda S, Terazawa S, Shimoda H, Imokawa G. β-Sitosterol 3-O-D-glucoside increases ceramide levels in the stratum corneum via the up-regulated expression of ceramide synthase-3 and glucosylceramide synthase in a reconstructed human epidermal keratinization model. PLoS One. 2021; 16(3): e0248150. https://doi.org/10.1371/journal.pone.0248150 |
| [17] | Huang HC, Chang TM. Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin. Int J Dermatol. 2008; 47(8), 812–819. https://doi.org/10.1111/j.1365-4632.2008.03687.x |
| [18] | Pérez-Acevedo G, Bosch-Alcaraz A, Torra-Bou JE. Efficacy and safety of a hyperoxygenated fatty acid compound in improving the microcirculation of purpura fulminans in paediatric patients with sepsis: a pilot study. Enferm Intensiva (Engl Ed). Published online July 30, 2023. https://doi.org/10.1016/j.enfie.2023.07.003 |
| [19] | Torra i Bou JE, Segovia Gómez T, Verdú Soriano J, Nolasco Bonmatí A, Rueda López J, Arboix i Perejamo M. The effectiveness of a hyperoxygenated fatty acid compound in preventing pressure ulcers. J Wound Care. 2005; 14(3): 117-121. https://doi.org/10.12968/jowc.2005.14.3.26752 |
| [20] | Lázaro-Martínez JL, López-Moral M, García-Alamino JM, Bohbot S, Sanz-Corbalán I, García-Álvarez Y. Evolution of the TcPO2 values following hyperoxygenated fatty acids emulsion application in patients with diabetic foot disease: results of a clinical trial. J Wound Care. 2021; 30(1): 74-79. https://doi.org/10.12968/jowc.2021.30.1.74 |
| [21] | Walker RM, Gillespie BM, Thalib L, Higgins NS, Whitty JA. Foam dressings for treating pressure ulcers. Cochrane Database Syst Rev. 2017; 10(10): CD011332. https://doi.org/10.1002/14651858.CD011332.pub2 |
| [22] | Westby MJ, Dumville JC, Soares MO, Stubbs N, Norman G. Dressings and topical agents for treating pressure ulcers. Cochrane Database Syst Rev. 2017; 6(6): CD011947. https://doi.org/10.1002/14651858.CD011947.pub2 |
| [23] | Moore ZE, Webster J. Dressings and topical agents for preventing pressure ulcers. Cochrane Database Syst Rev. 2018; 12(12): CD009362. https://doi.org/10.1002/14651858.CD009362.pub3 |
APA Style
Valenzuela, F., Altbir, C. R., Schatloff, D. H., Bustos, R., Moya, N. (2024). Use of Abzolem ® in Pressure Injuries: Experience of an Exploratory Study. International Journal of Clinical Dermatology, 7(1), 6-10. https://doi.org/10.11648/j.ijcd.20240701.12
ACS Style
Valenzuela, F.; Altbir, C. R.; Schatloff, D. H.; Bustos, R.; Moya, N. Use of Abzolem ® in Pressure Injuries: Experience of an Exploratory Study. Int. J. Clin. Dermatol. 2024, 7(1), 6-10. doi: 10.11648/j.ijcd.20240701.12
AMA Style
Valenzuela F, Altbir CR, Schatloff DH, Bustos R, Moya N. Use of Abzolem ® in Pressure Injuries: Experience of an Exploratory Study. Int J Clin Dermatol. 2024;7(1):6-10. doi: 10.11648/j.ijcd.20240701.12
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Download@article{10.11648/j.ijcd.20240701.12,
author = {Fernando Valenzuela and Catalina Retamal Altbir and Dan Hartmann Schatloff and Roberto Bustos and Nicolas Moya},
title = {Use of Abzolem ® in Pressure Injuries: Experience of an Exploratory Study},
journal = {International Journal of Clinical Dermatology},
volume = {7},
number = {1},
pages = {6-10},
doi = {10.11648/j.ijcd.20240701.12},
url = {https://doi.org/10.11648/j.ijcd.20240701.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcd.20240701.12},
abstract = {Introduction: Pressure injuries represent a significant and prevalent public health problem in bedridden and institutionalized patients. The correct management of pressure injuries is essential for preventing complications, enhancing patient well-being, and reducing the overall burden on healthcare systems. It underscores the importance of a holistic and patient-centered approach to wound care. Preventive measures and the action of a multidisciplinary team are essential to the correct treatment of pressure injuries. There are multiple active dressings and topical solutions to treat and protect the wounds, among them the hyperoxygenated fatty acids, such as Abzolem®. Objective: Evaluate and verify the effectiveness and safety of the use of Abzolem® in the treatment of patients with pressure injuries grade I and II. Materials and methods: an exploratory study was carried out on 6 patients residing in a long-term establishment in Santiago of Chile with grade I and II pressure injuries in which Abzolem® was used for twice-daily dressings. Results: The use of Abzolem® led to a significant improvement in grade I pressure injuries in 10 ± 3 days and grade II pressure injuries in 15 ± 3 days, without related adverse events and with good tolerance by patients. Conclusion: The use of hyperoxygenated fatty acids, such as Abzolem® corresponds to a safe therapeutic alternative, easy to apply, and effective in the treatment of grade I and II pressure injuries.
},
year = {2024}
}
TY - JOUR T1 - Use of Abzolem ® in Pressure Injuries: Experience of an Exploratory Study AU - Fernando Valenzuela AU - Catalina Retamal Altbir AU - Dan Hartmann Schatloff AU - Roberto Bustos AU - Nicolas Moya Y1 - 2024/02/20 PY - 2024 N1 - https://doi.org/10.11648/j.ijcd.20240701.12 DO - 10.11648/j.ijcd.20240701.12 T2 - International Journal of Clinical Dermatology JF - International Journal of Clinical Dermatology JO - International Journal of Clinical Dermatology SP - 6 EP - 10 PB - Science Publishing Group SN - 2995-1305 UR - https://doi.org/10.11648/j.ijcd.20240701.12 AB - Introduction: Pressure injuries represent a significant and prevalent public health problem in bedridden and institutionalized patients. The correct management of pressure injuries is essential for preventing complications, enhancing patient well-being, and reducing the overall burden on healthcare systems. It underscores the importance of a holistic and patient-centered approach to wound care. Preventive measures and the action of a multidisciplinary team are essential to the correct treatment of pressure injuries. There are multiple active dressings and topical solutions to treat and protect the wounds, among them the hyperoxygenated fatty acids, such as Abzolem®. Objective: Evaluate and verify the effectiveness and safety of the use of Abzolem® in the treatment of patients with pressure injuries grade I and II. Materials and methods: an exploratory study was carried out on 6 patients residing in a long-term establishment in Santiago of Chile with grade I and II pressure injuries in which Abzolem® was used for twice-daily dressings. Results: The use of Abzolem® led to a significant improvement in grade I pressure injuries in 10 ± 3 days and grade II pressure injuries in 15 ± 3 days, without related adverse events and with good tolerance by patients. Conclusion: The use of hyperoxygenated fatty acids, such as Abzolem® corresponds to a safe therapeutic alternative, easy to apply, and effective in the treatment of grade I and II pressure injuries. VL - 7 IS - 1 ER -
Department of Dermatology, University of Chile Clinical Hospital, Santiago, Chile; Department of Dermatology, International Center for Clinical Studies (CIEC), Santiago, Chile
