International Journal of Clinical Dermatology


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Zoon’s Balanitis (Balanitis Circumscripta Plasmacellularis) – a Case Report with a Review of Literature

Zoon's balanitis or balanitis circumscripta plasmacellularis is a rare, idiopathic, chronic, benign, inflammatory disease of the genital mucosa of non-sexually transmitted nature. Etiopathogenesis is not fully understood, but the moist environment and chronic irritation are considered as important triggers. It occurs mainly in uncircumcised middle- and elderly men, but there are single cases in circumcised men. Affects the glans penis and foreskin. It is also rarely seen in women, such as Zoon's vulvitis, with predilectation involvement of labia minora. The article presented an overview of epidemiology, clinical performance, histopathological characteristics, diagnostic criteria and diagnostic methods of Zoon's balanitis. In addition, the differential diagnosis of the disease is discussed. Treatment methods are considered and circumcision is highlighted as the "gold standard" and first choice. We present a 53-year-old man with a well-circumscribed erythematous plaques on the glans penis and the inner surface of the foreskin from 10 years. Histologically plasmocyte infiltrate is established. Based on the correlation of history, dermatological status and histopathological result was diagnosed Zoon's balanitis. Conservative topical therapy was our preferred way of treatment. On an outpatient basis, we recommended personal genital hygiene, mometasone furoate cream 0.1% for 2 weeks and tacrolimus 0.1% ointment for 1 month. A control examination after 1 and a half months found a good clinical result with mild residual erythema. The patient was explained both the need for regular clinical and histological monitoring due to the carcinogenic potential of the lesions and the option of therapeutic circumcision.

Zoon Balanitis, Circumcision, Nonvenereal Disease, Topical Calcineurin Inhibitors, Lasers

APA Style

Ivanka Temelkova, Valentina Broshtilova, Svetlana Bezhanova, Atanas Batashki, Yoanna Velevska, et al. (2023). Zoon’s Balanitis (Balanitis Circumscripta Plasmacellularis) – a Case Report with a Review of Literature. International Journal of Clinical Dermatology, 6(2), 14-17.

ACS Style

Ivanka Temelkova; Valentina Broshtilova; Svetlana Bezhanova; Atanas Batashki; Yoanna Velevska, et al. Zoon’s Balanitis (Balanitis Circumscripta Plasmacellularis) – a Case Report with a Review of Literature. Int. J. Clin. Dermatol. 2023, 6(2), 14-17. doi: 10.11648/j.ijcd.20230602.11

AMA Style

Ivanka Temelkova, Valentina Broshtilova, Svetlana Bezhanova, Atanas Batashki, Yoanna Velevska, et al. Zoon’s Balanitis (Balanitis Circumscripta Plasmacellularis) – a Case Report with a Review of Literature. Int J Clin Dermatol. 2023;6(2):14-17. doi: 10.11648/j.ijcd.20230602.11

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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